Sabine Felser

Overview
Related items

About Sabine Felser:

No description specified

SEEK ID: https://ldh.mediz-rostock.imise.uni-leipzig.de/people/9

Location: Germany

ORCID: https://orcid.org/0000-0002-4882-0468

Joined: 7th Nov 2024

Expertise: Not specified

Tools: Not specified

Their tags

This person has not yet tagged anything.

Related items

Advanced Programmes list for this Person with search and filtering

Universitätsmedizin Rostock (UMR)

Wir verbinden Tradition mit Innovation. Wir sind stolz auf unsere lange Tradition seit 1419 und arbeiten im Sinne von „Traditio et Innovatio“ dafür, Krankheiten vorzubeugen, Patienten zu heilen und ihre Lebensqualität zu wahren. Wir forschen für den Menschen. Als einer der größten Arbeitgeber des Landes sind wir ein starker Partner für die Hansestadt Rostock und Mecklenburg-Vorpommern.

Wir stellen die Menschen in den Mittelpunkt. Wir verstehen unsere medizinische Arbeit als Dienst am ...

Projects:

Web page: https://www.med.uni-rostock.de/

Advanced Projects list for this Person with search and filtering

Individuelles Heimtraining für Patienten mit Kopf-Halstumoren - eine multizentrische Studie zur Verbesserung der Lebensqualität (HeiKo-Studie)

Kopf-Hals-Tumorpatienten in der Nachsorge erhielten ein individuelles Heimtrainingsprogramm (Mobilisations-, Koordinations-, Dehnungs- und Kräftigungsübungen) inkl. Empfehlungen zum Ausdauertraining. Über 12 Wochen (Intervention) wurden die Patienten einmal wöchentlich von einem Bewegungstherapeuten angerufen. Das absolvierte Training wurde in einem Trainingstagebuch erfasst, ebenso unerwünschte Ereignisse, das Wohlbefinden und die Motivation zum Training. Vor und nach der 12-wöchigen Intervention ...

Programme: Universitätsmedizin Rostock (UMR)

Public web page: Not specified

Organisms: Not specified

Körperliches Wohlbefinden und Bewegungsverhalten von Patientinnen und Patienten mit Myeloproliferativen Neoplasien (MPN) oder Mastozytose - OSHO #97

Mittels Patientenbefragung (analog und online) wurde erfasst, wie a) das körperliche Wohlbefinden und das Bewegungsverhalten von Patienten mit MPN oder Mastozytose ist, b) welche Symptome / Nebenwirkungen / Begleiterkrankungen und Ängste die Patienten in ihrer körperlichen Aktivität einschränken sowie c) wie hoch die Motivation zu körperlicher Aktivität ist und welche Präferenzen diese Patientenkohorte hat. Ziel war es spezifische Trainingsempfehlungen für diese Patientenkohorte zu erarbeiten.

Programme: Universitätsmedizin Rostock (UMR)

Public web page: Not specified

Organisms: Not specified

Advanced Institutions list for this Person with search and filtering

Medizinische Klinik III Hämatologie, Onkologie, Palliativmedizin

Country: Germany

City: Rostock

Web page: https://www.onkologie.med.uni-rostock.de

Universitätsmedizin Rostock

Country: Germany

City: Rostock

Web page: https://www.med.uni-rostock.de/

Advanced Data files list for this Person with search and filtering

Datenbank_HeiKo_final

Individuelles Heimtraining für Patienten mit Kopf-Halstumoren - eine multizentrische Studie zur Verbesserung der Lebensqualität (HeiKo-Studie)

Datenbereitstellung für unterschieldiche gemessene Paramter pro Studienteilnehemer für alle beteiligten Standorte inklusive der Auswertung der Daten.

Creator: Sabine Felser

Submitter: Marco Stubbe

Download

Created: 25th Mar 2025 at 06:33

1 hidden item

Advanced Publications list for this Person with search and filtering

Feasibility of individualized home exercise programs for patients with head and neck cancer-study protocol and first results of a multicentre single-arm intervention trial (OSHO #94).

Individuelles Heimtraining für Patienten mit Kopf-Halstumoren - eine multizentrische Studie zur Verbesserung der Lebensqualität (HeiKo-Studie)

Abstract (Expand)

INTRODUCTION: Patients with head and neck cancer (PwHNC) benefit from targeted exercise interventions: symptom relief, compensation for dysfunction, improvement in quality of life (QoL). Data on … acceptance physical interventions in PwHNC are rare. The 'OSHO #94' trial investigates the short- and medium-term effects of individualized home exercise in PwHNC on QoL, physical activity and functionality. The study includes a feasibility phase (proof of concept) in order to evaluate the acceptance. Here we present the study protocol as well as the feasibility results. METHODS AND ANALYSIS: This prospective, multicentre, single-arm intervention study includes PwHNC >/=18 years of age in aftercare or palliative care with stable remission under immunotherapy. The study opened in January 01, 2021, with estimated completion by December 31, 2024. The PwHNC receive an individualized home exercise program consisting of mobilization, coordination, strengthening and stretching exercises. This should be carried out at least three times a week over 12 weeks for 15 to 30 minutes, supplemented by aerobic training two to three times a week for 30 minutes (intervention). Once weekly telephone calls with a physiotherapist are performed. Subsequently, there is a 12-week follow-up (FU) without exercise specifications/contact. Outcomes are measured before and after the intervention and following the FU. Primary outcome of the feasibility phase (n = 25) was the determination of the dropout rate during the intervention with a termination cut off if more than 30% PwHNC withdrew premature. The primary outcome of the OSHO #94' trial (N = 53) is the change in global QoL score from pre- to post-intervention (EORTC QLQ-C30). Secondary outcomes include clinical and patient-reported measures, training details as well as functional diagnostic data (e.g. level of physical activity, training frequency, flexibility, fall risk and aerobic performance). RESULTS: 25 PwHNC were enrolled onto the feasibility cohort. Only16% (4/25 patients) did not complete the study. Therefore, recruitment of PwHNC was continued. The dropout rate was adjusted from 30% (N = 60) to 20% (N = 53, calculated sample size n = 42 PwHNC and 20% (n = 11) to dropout). CONCLUSIONS: Individualized home exercise programs in PwHNC in aftercare seem feasible. Consequently, the aim is now to evaluate the short and medium-term effects of individualized home exercise.

Authors: S. Felser, J. Rogahn, A. Glass, L. A. Bonke, D. F. Struder, J. Stolle, S. Schulze, M. Blaurock, U. Kriesen, C. Junghanss, C. Grosse-Thie

Date Published: 22nd Aug 2024

Publication Type: Journal

PubMed ID: 39173016

Citation: PLoS One. 2024 Aug 22;19(8):e0301304. doi: 10.1371/journal.pone.0301304. eCollection 2024.

Created: 25th Mar 2025 at 06:35

Physical exercise recommendations for patients with chronic myeloid leukemia based on individual preferences identified in a large international patient survey study of the East German Study Group for Hematology and Oncology (OSHO #97).

Körperliches Wohlbefinden und Bewegungsverhalten von Patientinnen und Patienten mit Myeloproliferativen Neoplasien (MPN) oder Mastozytose - OSHO #97

Abstract (Expand)

BACKGROUND: Tyrosine kinase inhibitors (TKIs) have significantly lowered mortality of chronic myeloid leukemia (CML) patients adjusting life expectancy to that of the standard population. However, CML … and its treatment with TKIs causes a high disease burden. Physical exercise (PE) could be a non-pharmacological approach to reducing these and improving quality of life. PURPOSE: The aim of this study was to determine the individual disease burden as well as PE preferences of CML patients and to deduce thereof specific PE recommendations. METHODS: This multicenter survey was conducted in cooperation with the LeukaNET/Leukemia-patient network including CML patients aged >/=18 years (German Registry of Clinical Trials, DRKS00023698). The severity of selected symptoms was assessed using the adapted Myeloproliferative Neoplasms Symptom Assessment Form: 0 (absent), 1-30 (mild), 31-70 (moderate), or 71-100 (severe). Information about patients' PE needs and preferences depending on their motivation was recorded. RESULTS: A total of 212 questionnaires were analyzed (52% female, median age 54 years). The prevalence of moderate-to-severe symptoms was 49% for fatigue, 40% for musculoskeletal pain, and 37% for concentration problems. Other commonly reported symptoms included skin reactions (42%) and weight gain (24%). The proportion of overweight/obese patients was 52%. Half of all respondents requested more information regarding PE. Patients with CML preferred individual training (82%), located outdoors (71%), at home (47%), or in an indoor swimming pool (31%). Regarding the training frequency, sports-inactive patients preferred a frequency of 1-2 training sessions per week, whereas sports-active patients preferred 3-4 sessions per week (p <0.001). Sports-inactive patients preferred a training time of 15-45 minutes, while sports-active patients preferred 30-60 minutes (p = 0.002). Subsequently, PE recommendations were developed for patients with CML. Combined resistance and endurance training (moderate intensity twice per week for 30 minutes) was recommended for beginners. Obese patients should prioritize joint-relieving sports. To reduce the risk of skin reactions, direct sunlight and possibly water sports should be avoided, and UV protection should be used. CONCLUSION: Counseling and motivation of CML patients to be physically active should be part of the standard of care as well as support for implementation.

Authors: L. Hollenbach, J. Rogahn, P. le Coutre, S. Schulze, L. O. Muegge, J. Geissler, J. Gruen, C. Junghanss, S. Felser

Date Published: 7th Mar 2024

Publication Type: Journal

PubMed ID: 38450192

Citation: Front Oncol. 2024 Feb 21;14:1345050. doi: 10.3389/fonc.2024.1345050. eCollection 2024.

Created: 25th Nov 2024 at 07:34

Physical exercise recommendations for patients with polycythemia vera based on preferences identified in a large international patient survey study of the East German Study Group for Hematology and Oncology (OSHO #97).

Körperliches Wohlbefinden und Bewegungsverhalten von Patientinnen und Patienten mit Myeloproliferativen Neoplasien (MPN) oder Mastozytose - OSHO #97

Abstract (Expand)

BACKGROUND: Exercise therapy during cancer treatment reduces symptom burden and improves quality of life (QoL). Polycythemia vera (PV) is a myeloproliferative neoplasia associated with good overall … survival (up to decades) but a significant symptom burden, including thromboembolic events and dysesthesias. There are no specific exercise recommendations for patients with PV. Thus, we aimed to determine the exercise preferences of patients with PV and to derive specific recommendations based on the most commonly reported symptoms. METHODS: This multicenter survey included patients with PV >/=18 years old. Demographic, clinical, and disease burden data were collected. The severity of selected symptoms was assessed using the adapted Myeloproliferative Neoplasms Symptom Assessment Form: 0 (absent), 1-30 (mild), 31-70 (moderate), or 71-100 (severe). The patients' information needs about physical activity (PA) and exercise preferences were recorded depending on their motivation and analyzed with regard to demographic aspects. RESULTS: The sample comprised 182 patients (68% female, 61 +/- 12 years). The prevalence of moderate-to-severe symptoms was 60% for fatigue, 44% for concentration problems, and 35% for bone/muscle pain. Other commonly reported symptoms included skin reactions (49%), splenomegaly (35%), and increased bleeding tendency (28%). Overall, 67% of respondents requested more information regarding PA. Patients with PV preferred individual training (79%) located outdoors (79%) or at home (56%). Regarding the amount of training, sports-inactive patients preferred a frequency of 1-2 times/week and session durations of 15-45 min, whereas sports-active patients preferred 3-4 times/week and 30-60 min (p < 0.001). Higher sport-inactiveness was observed in patients with lower educational level compared to patients with higher educational level (69% vs. 50%, p = 0.021). For beginners, combined resistance-endurance (circuit) training two times/week, which can be performed outdoors or at home, should be recommended. In the case of splenomegaly or bleeding symptoms, exercises with a low injury risk should be chosen. CONCLUSION: PA is important for patients with PV; therefore, counseling should be integrated into the treatment plan. Specifically, patients with low educational level should be addressed. Prospective studies are warranted to evaluate the effects of the novel exercise recommendations.

Authors: S. Felser, J. Rogahn, L. Hollenbach, J. Gruen, P. le Coutre, H. K. Al-Ali, S. Schulze, L. O. Muegge, V. Kraze-Kliebhahn, C. Junghanss

Date Published: 4th Oct 2023

Publication Type: Journal

PubMed ID: 37559463

Citation: Cancer Med. 2023 Sep;12(17):18235-18245. doi: 10.1002/cam4.6413. Epub 2023 Aug 9.

Created: 25th Nov 2024 at 07:35

Anxieties, age and motivation influence physical activity in patients with myeloproliferative neoplasms - a multicenter survey from the East German study group for hematology and oncology (OSHO #97).

Körperliches Wohlbefinden und Bewegungsverhalten von Patientinnen und Patienten mit Myeloproliferativen Neoplasien (MPN) oder Mastozytose - OSHO #97

Abstract (Expand)

BACKGROUND: Physical activity (PA) is a non-pharmacological approach to alleviate symptom burden and improve health-related quality of life (HrQoL) in cancer patients (pts). Whether pts with …

Authors: S. Felser, J. Rogahn, P. le Coutre, H. K. Al-Ali, S. Schulze, L. O. Muegge, J. Gruen, J. Geissler, V. Kraze-Kliebhahn, C. Junghanss

Date Published: 23rd Jan 2023

Publication Type: Journal

PubMed ID: 36686756

Citation: Front Oncol. 2023 Jan 4;12:1056786. doi: 10.3389/fonc.2022.1056786. eCollection 2022.

Created: 25th Nov 2024 at 07:36

Association Between Cancer-Related Fatigue and Falls in Patients With Myeloproliferative Neoplasms: Results of a Multicenter Cross-Sectional Survey From the East German Study Group for Hematology and Oncology (OSHO #97).

Körperliches Wohlbefinden und Bewegungsverhalten von Patientinnen und Patienten mit Myeloproliferativen Neoplasien (MPN) oder Mastozytose - OSHO #97

Abstract (Expand)

OBJECTIVE: This study retrospectively examined the association between cancer-related fatigue (CrF) and the number of falls during the last 12 months in patients with myeloproliferative neoplasms (MPNs). …

Authors: S. Felser, M. Gube, J. Gruen, P. I. Coutre, S. Schulze, L. O. Muegge, C. Junghanss, S. Ulbricht

Date Published: 21st Dec 2022

Publication Type: Journal

PubMed ID: 36539979

Citation: Integr Cancer Ther. 2022 Jan-Dec;21:15347354221143064. doi: 10.1177/15347354221143064.

Created: 25th Nov 2024 at 07:36