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Körperliches Wohlbefinden und Bewegungsverhalten von Patientinnen und Patienten mit Myeloproliferativen Neoplasien (MPN) oder Mastozytose - OSHO #97
Individuelles Heimtraining für Patienten mit Kopf-Halstumoren - eine multizentrische Studie zur Verbesserung der Lebensqualität (HeiKo-Studie)

Institutions: Medizinische Klinik III Hämatologie, Onkologie, Palliativmedizin, Universitätsmedizin Rostock

https://orcid.org/0000-0002-4882-0468

Marco Stubbe

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Institutions: Medizinisches Datenintegrationszentrum Rostock (MeDIZ.Rostock), Universitätsmedizin Rostock

https://orcid.org/0009-0000-8875-8892

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Universitätsmedizin Rostock (UMR)

Wir verbinden Tradition mit Innovation. Wir sind stolz auf unsere lange Tradition seit 1419 und arbeiten im Sinne von „Traditio et Innovatio“ dafür, Krankheiten vorzubeugen, Patienten zu heilen und ihre Lebensqualität zu wahren. Wir forschen für den Menschen. Als einer der größten Arbeitgeber des Landes sind wir ein starker Partner für die Hansestadt Rostock und Mecklenburg-Vorpommern.

Wir stellen die Menschen in den Mittelpunkt. Wir verstehen unsere medizinische Arbeit als Dienst am ...

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Web page: https://www.med.uni-rostock.de/

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Individuelles Heimtraining für Patienten mit Kopf-Halstumoren - eine multizentrische Studie zur Verbesserung der Lebensqualität (HeiKo-Studie)

Kopf-Hals-Tumorpatienten in der Nachsorge erhielten ein individuelles Heimtrainingsprogramm (Mobilisations-, Koordinations-, Dehnungs- und Kräftigungsübungen) inkl. Empfehlungen zum Ausdauertraining. Über 12 Wochen (Intervention) wurden die Patienten einmal wöchentlich von einem Bewegungstherapeuten angerufen. Das absolvierte Training wurde in einem Trainingstagebuch erfasst, ebenso unerwünschte Ereignisse, das Wohlbefinden und die Motivation zum Training. Vor und nach der 12-wöchigen Intervention ...

Programme: Universitätsmedizin Rostock (UMR)

Public web page: Not specified

Organisms: Not specified

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Feasibility of individualized home exercise programs for patients with head and neck cancer-study protocol and first results of a multicentre single-arm intervention trial (OSHO #94).

Individuelles Heimtraining für Patienten mit Kopf-Halstumoren - eine multizentrische Studie zur Verbesserung der Lebensqualität (HeiKo-Studie)

Abstract (Expand)

INTRODUCTION: Patients with head and neck cancer (PwHNC) benefit from targeted exercise interventions: symptom relief, compensation for dysfunction, improvement in quality of life (QoL). Data on … acceptance physical interventions in PwHNC are rare. The 'OSHO #94' trial investigates the short- and medium-term effects of individualized home exercise in PwHNC on QoL, physical activity and functionality. The study includes a feasibility phase (proof of concept) in order to evaluate the acceptance. Here we present the study protocol as well as the feasibility results. METHODS AND ANALYSIS: This prospective, multicentre, single-arm intervention study includes PwHNC >/=18 years of age in aftercare or palliative care with stable remission under immunotherapy. The study opened in January 01, 2021, with estimated completion by December 31, 2024. The PwHNC receive an individualized home exercise program consisting of mobilization, coordination, strengthening and stretching exercises. This should be carried out at least three times a week over 12 weeks for 15 to 30 minutes, supplemented by aerobic training two to three times a week for 30 minutes (intervention). Once weekly telephone calls with a physiotherapist are performed. Subsequently, there is a 12-week follow-up (FU) without exercise specifications/contact. Outcomes are measured before and after the intervention and following the FU. Primary outcome of the feasibility phase (n = 25) was the determination of the dropout rate during the intervention with a termination cut off if more than 30% PwHNC withdrew premature. The primary outcome of the OSHO #94' trial (N = 53) is the change in global QoL score from pre- to post-intervention (EORTC QLQ-C30). Secondary outcomes include clinical and patient-reported measures, training details as well as functional diagnostic data (e.g. level of physical activity, training frequency, flexibility, fall risk and aerobic performance). RESULTS: 25 PwHNC were enrolled onto the feasibility cohort. Only16% (4/25 patients) did not complete the study. Therefore, recruitment of PwHNC was continued. The dropout rate was adjusted from 30% (N = 60) to 20% (N = 53, calculated sample size n = 42 PwHNC and 20% (n = 11) to dropout). CONCLUSIONS: Individualized home exercise programs in PwHNC in aftercare seem feasible. Consequently, the aim is now to evaluate the short and medium-term effects of individualized home exercise.

Authors: S. Felser, J. Rogahn, A. Glass, L. A. Bonke, D. F. Struder, J. Stolle, S. Schulze, M. Blaurock, U. Kriesen, C. Junghanss, C. Grosse-Thie

Date Published: 22nd Aug 2024

Publication Type: Journal

PubMed ID: 39173016

Citation: PLoS One. 2024 Aug 22;19(8):e0301304. doi: 10.1371/journal.pone.0301304. eCollection 2024.

Created: 25th Mar 2025 at 06:35

Datenbank_HeiKo_final
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Creator

Submitter

Version History

Version 1 (earliest) Created 25th Mar 2025 at 06:33 by Marco Stubbe

Datenbank_HeiKo_final Version 1

Creator

Submitter

Version History

Version 1 (earliest) Created 25th Mar 2025 at 06:33 by Marco Stubbe

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Datenbank_HeiKo_final
Version 1